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Recurrent IVF Failure

Specialised care for recurrent IVF failure by Dr. P. Srilekha. Immunological evaluation, ERA testing and personalised protocols for success in Hyderabad.

150+Cases Managed
4+Years Exp.
70%Improved Outcome
Recurrent IVF Failure

Overview

Recurrent IVF failure is defined as three or more failed IVF cycles despite good-quality embryos. It is a distressing situation that requires systematic evaluation to identify correctable underlying causes before attempting further cycles.

Dr. P. Srilekha coordinates a comprehensive recurrent IVF failure workup addressing uterine factors, embryo quality, immunological issues and thrombophilia - developing a personalised protocol to maximise the chances of success in subsequent cycles.

Symptoms & Conditions We Treat

Failed Embryo Implantation

Good quality embryos failing to implant despite transfer

3+ Failed IVF Cycles

Multiple unsuccessful IVF attempts with no live birth

Chemical Pregnancies

Positive tests that do not progress past early stages

Embryo Quality Issues

Poor embryo development or chromosomal abnormalities

Uterine Abnormalities

Structural issues identified or suspected after failure

Immunological Factors

Autoimmune issues affecting implantation success

Our Treatment Approach

1

Detailed History Review

Thorough analysis of all previous cycles including stimulation response, embryo quality and endometrium.

2

Advanced Investigation Panel

ERA test, hysteroscopy, thrombophilia screen, immunological tests and sperm DNA fragmentation.

3

Modified Protocol Design

New stimulation approach, endometrial preparation, or adjuvant therapies based on findings.

4

Support and Monitoring

Enhanced luteal support, close monitoring and emotional support throughout the cycle.

Treatment Options

Genetic Testing

  • PGT-A (chromosomal screening)
  • PGT-M (single gene)
  • Sperm DNA fragmentation
  • Karyotyping

Uterine Evaluation

  • Hysteroscopy
  • Endometrial biopsy
  • ERA (implantation timing)
  • Saline sonography

Immunological Treatment

  • Intralipid infusion
  • Steroids protocol
  • IVIG therapy
  • Anticoagulation

Modified IVF Protocol

  • Freeze-all strategy
  • Blastocyst culture
  • Assisted hatching
  • Donor egg consideration

Why Choose Srilekha's Clinic?

Specialist Evaluation

Systematic investigation to find what has been missed

Comprehensive Testing

ERA, immunological and genetic workup as standard

Emotional Support

Understanding and compassionate care after repeated loss

Evidence-Based Adjuvants

Using proven adjuvant therapies where evidence supports

New Strategy

Fresh eyes and a modified approach for each new cycle

Holistic Care

Addressing physical and psychological aspects together

Gynaecology FAQ

Frequently Asked Questions

Quick answers about this condition. Can't find what you need? Chat with us directly.

Recurrent IVF failure (RIF) is defined as 3 or more failed IVF cycles with good-quality embryos transferred without achieving an ongoing pregnancy.

Causes: embryo chromosomal abnormalities, uterine factors (polyps, fibroids, thin endometrium), implantation failure, thrombophilia, immunological causes, and unexplained factors.

Tests: hysteroscopy, ERA (Endometrial Receptivity Array), PGT-A (embryo genetic testing), thrombophilia screen, immunological testing (NK cells), and karyotyping of both partners.

ERA identifies the optimal "window of implantation" using endometrial biopsy genomics. A personalised embryo transfer timed to ERA results improves implantation rates after prior failure.

Yes. With thorough investigation and tailored management, many couples with RIF achieve successful pregnancy. Dr. Srilekha provides individualised, evidence-based treatment.

Book via WhatsApp +91 9963 138 139. Dr. Srilekha at Habsiguda, Hyderabad.