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Fertility

Immunomodulation Treatment

Immunomodulation therapy for recurrent IVF failure and recurrent miscarriage by Dr. P. Srilekha. Intralipid, IVIG and steroid protocols in Hyderabad.

100+Cases Treated
4+Years Exp.
ImprovedImplantation
Immunomodulation Treatment

Overview

Immunomodulation in reproductive medicine addresses immune dysfunction that causes recurrent implantation failure and pregnancy loss. Conditions such as elevated NK cells, antiphospholipid syndrome and thyroid autoimmunity are treatable causes.

Dr. P. Srilekha assesses the immune profile of women with recurrent IVF failure or miscarriage and offers targeted immunotherapy - including intralipid infusion, low-dose aspirin, heparin and steroids - to improve implantation and pregnancy outcomes.

Symptoms & Conditions We Treat

Recurrent Implantation Failure

3+ failed IVF cycles with good embryos

Recurrent Miscarriage

2 or more consecutive pregnancy losses

Elevated NK Cells

High uterine natural killer cell activity on biopsy

Antiphospholipid Syndrome

Antibodies causing blood clotting and pregnancy loss

Thyroid Antibodies

Elevated anti-TPO or anti-thyroglobulin affecting implantation

Autoimmune Conditions

Underlying autoimmune disease affecting reproductive outcome

Our Treatment Approach

1

Immune Panel Testing

NK cell assay, antiphospholipid antibodies, thyroid antibodies, ANA and cytokine profile.

2

Results Interpretation

Clinical correlation of immune results with treatment history to determine intervention.

3

Immunotherapy Protocol

Evidence-based protocol: intralipid, IVIG, prednisolone, aspirin or heparin as indicated.

4

Cycle Monitoring

Close monitoring during IVF cycle with endometrial assessment and luteal support.

Treatment Options

Intralipid Infusion

  • 20% lipid emulsion IV infusion
  • Reduces NK cell activity
  • Given before embryo transfer
  • Repeat during luteal phase

IVIG Therapy

  • For severe immune dysfunction
  • High-cost but effective
  • Administered before transfer
  • Repeat in early pregnancy

Anticoagulation

  • Low-dose aspirin 75mg
  • LMWH (clexane) for APS
  • Continued into pregnancy
  • Thrombophilia management

Steroid Protocol

  • Prednisolone 5-25mg from stimulation
  • Dexamethasone for specific cases
  • Hydroxychloroquine for autoimmune
  • Tapering in pregnancy

Why Choose Srilekha's Clinic?

Expert Gynaecologist

MS (OBG) specialist with 4+ years dedicated to women health in Hyderabad

Personalised Care

Treatment tailored to your age, diagnosis, and fertility plans

Advanced Diagnostics

Comprehensive hormonal, ultrasound and imaging workup

Fertility-Preserving

Treatments designed to protect and support future fertility

Flexible Appointments

Weekday and weekend slots available

Compassionate Care

A safe, respectful space where you feel heard and understood

Neurology FAQ

Frequently Asked Questions

Quick answers about this condition. Can't find what you need? Chat with us directly.

Immunomodulation uses drugs or therapies to modify the immune system to treat autoimmune neurological diseases like MS, myasthenia gravis, CIDP, autoimmune encephalitis, and neuromyelitis optica.

Therapies include corticosteroids, IVIG, plasmapheresis, interferon-beta, natalizumab, rituximab, ocrelizumab, azathioprine, and mycophenolate.

Most are well-tolerated with regular monitoring — blood counts, liver function, and renal function checked periodically.

Intravenous immunoglobulin (IVIG) rapidly modulates immune response and is used for GBS, CIDP, myasthenia gravis crises, and inflammatory neuropathies.

Book via WhatsApp +91 9963 138 139. Dr. Bharath Kumar at Habsiguda, Hyderabad, Mon–Sun 9 AM–8 PM.