Apomorphine injection therapy for advanced Parkinson disease by Dr. Bharath Kumar Surisetti. Effective off-period rescue treatment in Hyderabad.
Apomorphine is a potent dopamine agonist administered by subcutaneous injection to rescue patients with advanced Parkinson disease from unpredictable off-period episodes. It acts within 5-10 minutes, providing rapid, reliable motor benefit when oral levodopa is failing.
Dr. Bharath Kumar Surisetti provides comprehensive apomorphine therapy including supervised test dosing, patient and carer training in self-injection technique, dose titration and long-term follow-up, significantly improving quality of life for patients with disabling motor fluctuations.
Sudden loss of Parkinson medication effect causing severe immobility, rigidity and tremor
Inability to initiate walking or sudden stopping mid-stride during off periods
Unpredictable or prolonged delay in levodopa absorption causing long off periods
Unpredictable on-off switching despite optimised oral therapy in advanced Parkinson disease
Prolonged overnight off state before first morning dose takes effect
Rapid alternation between dyskinesias during on phase and rigidity during off phase
Detailed documentation of off-period frequency, duration and severity to quantify treatment need.
Supervised subcutaneous test dose with domperidone pre-treatment to assess response and tolerability.
Patient and carer training on subcutaneous self-injection technique, site rotation and pen device use.
Individual dose optimisation with regular clinic review to adjust frequency and manage side effects.
Dr. Bharath Kumar Surisetti has 9+ years specialising in Parkinson disease and complex motor fluctuations
Safe apomorphine challenge performed in clinic with monitoring to confirm response before prescribing
Consistent rescue from off periods with apomorphine rescue injection therapy
Thorough injection technique education for both patient and family caregivers
Structured clinic reviews to titrate dose and ensure sustained benefit over time
Apomorphine therapy integrated with complete Parkinson disease management programme
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Apomorphine is a fast-acting dopamine agonist given by subcutaneous injection or continuous pump infusion. It is used in advanced Parkinson's disease for "off" rescue therapy.
It works within 5–10 minutes of subcutaneous injection — much faster than oral levodopa — making it ideal for sudden, unpredictable "off" periods.
The continuous subcutaneous apomorphine pump delivers constant dopaminergic stimulation throughout the day, smoothing motor fluctuations and reducing total "off" time.
Common: nausea (prevented by domperidone pretreatment), local skin reactions, orthostatic hypotension, drowsiness. Impulse control disorders can occur with dopamine agonists.
Patients with advanced Parkinson's, significant motor fluctuations, or frequent "off" episodes not controlled by optimised oral therapy.
Book via WhatsApp +91 9963 138 139. Dr. Bharath Kumar at Habsiguda, Hyderabad.